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Discrepancies between Aldy results from BAM vs VCF files (hg19 reference genome)

2

Dear Aldy Team, I analyzed targeted sequencing data of 100 PGx genes aligned to the hg19 reference genome using both BAM and VCF files in Aldy v4.4 (Python 3.9.7 on...

paraveeown

Aldy test error

5

I run aldy test get the error result:

TuBieJun

Aldy v4.4 incorrectly calls GeT-RM sample NA21781 that was correctly called by Aldy v2.2.6

1

Hello there, while testing Aldy v4.4 on CYP2D6-calling on samples from [GeT-RM](https://www.ebi.ac.uk/ena/browser/view/PRJEB19931) I encountered something unexpected. On a [publication](https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1002/cpt.2173) that used Aldy v2.2.6, sample NA21781 is correctly genotyped as *2x2/*68+*4...

VasilisFlouris