Zachary Pincus

**Description**: Getting the socket options `REQ_CORRELATE` or `REQ_RELAXED` fails. Setting these options works fine. Getting other int-valued options works fine too. **Configuration**: I verified the error with pyzmq 17.0.0 and...

Canonical tautomer choice depends on stereochemistry elsewhere in the molecule

1

**Describe the bug** I have found a number of examples where the choice of which tautomer is canonical depends on stereochemistry elsewhere in the molecule. I think this behavior is...

Tautomer enumeration can halt too soon when stereochemistry is present / not ignored

1

**Describe the bug** Tautomer enumeration appears to not always go to completion when `RemoveSp3Stereo` is disabled. _[Edit: or maybe when there's any stereochemistry at all that's not being ignored/removed; see...

failures in canonicalizing smiles

1

**Describe the bug** Once a SMILES string is canonicalized, further rounds of canonicalizing that string should not produce different SMILES. Yet even with rdkit 2022.09.2 there are cases where this...