Zeta Mui

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This is a sample with normal values (most values close to 0): ![Normal_1](https://user-images.githubusercontent.com/28396680/159734723-3fcab77b-3d39-4d3e-83ec-a63a3a3bed00.PNG) The cnr log2 values density: ![Normal_1_cnr_log2_ratio_density](https://user-images.githubusercontent.com/28396680/161235139-7f542d2a-9ba8-47ef-88ba-326c657a05b3.png) The cns log2 values density: ![Normal_1_cns_log2_ratio_density](https://user-images.githubusercontent.com/28396680/161235183-94f5b8b9-f855-4e96-bb11-2d64db2fa840.png) All of these samples below...

> Hi @zetamui , > > Thanks for your detailed issue ! => I see you are using a very old version of CNVkit --> Try to update 1st if...