Griffen Wakelin

A potential workaround for people might be [here](https://programmerah.com/the-sparse-matrix-of-r-language-is-too-large-to-be-used-as-matrix-8856/) which worked for me on a node with 128G of RAM (this worked the second time I tried it, as the first...

> > A potential workaround for people might be [here](https://programmerah.com/the-sparse-matrix-of-r-language-is-too-large-to-be-used-as-matrix-8856/) which worked for me on a node with 128G of RAM (this worked the second time I tried it, as...

Your cell type annotations need to be in a column of your `adata_sc.obs` (single cell data). Based on your code, I assume they are in the `adata.obs['leiden']` column. You should...

> Thanks @wakelin-g. "if you are analysing MERFISH data, you should be using density_prior = uniform instead of density_prior = rna_count_based." Can you clarify to me, MERFISH/Xenium datasets will use...