Sirarat Sarntivijai

modeling cohort, no individual data available?

2

Is there a trick to using phenopacket to model patient's information at population level? E.g. Cohort of 150 colorectal carcinoma patients with hypertension phenotype?

restructure mouse strain classes in EFO

5

a substrain of a parent strain is not a 'is_a' relationship. Fix the classification, use related_to (or some loose property) to infer grouping. check BFO related_to definition for domian-range restriction...

Review response to drug hierarchy for GO vs EFO terms

11

As a general rule, if a drug is available in Chebi, the corresponding 'response to' term should be created in GO and imported into EFO. Review all subclasses of response...

Need a modelling decision for susceptibility to x.

5

ORDO uses predisposition to not susceptibility to. Investigate whether this term is used synonymously with susceptibility to in ORDO e.g. susceptibility to viral disease, and externally e/g/ in OMIM. This...

Many cell line cell entries are missing neccessary annotations (organism, cell type, disease, etc). They only contains ATCC xRef via seeAlso property. This is a major fault.