shenmskcc comments

Repositories
Issues
Comments

Results 3 comments of


                                            shenmskcc

Purity estimate =NA despite copy numbers present

the hyper-segmentation can affect downstream copy number and purity estimation. On Thu, Nov 14, 2019 at 11:28 AM Georgette Tanner wrote: > Hi > I've noticed that the majority of...

Log likelihood reported may be negative

It is hard to diagnose the problem why you get a very large log-likelihood in the first run without seeing the data. The flags suggest a noisy sample/low purity. These...

Log likelihood reported may be negative

The second run is indeed the better call. The first one systematically overcalls LOH with reduced cellular fractions across the board. The sparsity of het SNPs and the complexity of...