pgaudet

- [ ] NTR ~transposon silencing by piRNA-directed DNA methylation~ -> transposon silencing by piRNA-directed heterochromatin formation -> ++ transposon silencing by piRNA-directed transposon transcript destabilization (https://pubmed.ncbi.nlm.nih.gov/33419460/) https://pubmed.ncbi.nlm.nih.gov/32674113/

- [ ] NTR piRNA-mediated transposon silencing - [ ] NTR tRNA-mediated transposon silencing https://pubmed.ncbi.nlm.nih.gov/33789107/ see https://github.com/geneontology/go-ontology/issues/24561

NTR piRNA amplification loop PMID:23706823

Note that piRNA is mediated by polII (are there other polymerases than transcribe piRNAs?)

Dear all, The proposal has been made to obsolete 'GO:0034588 piRNA catabolic process'. The reason for obsoletion is that there is not evidence that this process exists; ie that piRNAs...

GO:1990511 - [x] Changed label piRNA biosynthetic process -> to piRNA processing - [x] Changed definition - old def: : "The chemical reactions and pathways resulting in the formation of...

From https://pubmed.ncbi.nlm.nih.gov/34724117/ > piRNAs can be categorized into primary piRNAs and secondary piRNAs based on their biogenesis pathways, which are principally distinguished by their mechanisms of 5′end formation. **Primary piRNAs**...

@gantonazzo From my reading (see pasted text above, among other references), the ping-pong amplification is part of 'secondary piRNAs processing' ; should we create 'primary piRNA processing' and 'secondary piRNA...

Right, it would be 'Secondary piRNA processing', see my comment just above

Do all the small RNAs go through this amplification process? I thought the siRNAs did, but not the miRNAs. I think we need to review that branch to make sure...