pgaudet

Your proposed definition for GO:0060395 SMAD protein signal transduction, "The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD...

> I don't know if we want/need terms specific for di/tri methylation as I am not sure if different enzymes perform these modifications, or that if a methyl transfer are...

@Antonialock was asking generally, "could you obsolete all the transcription regulatory terms that we "shouldn't" annotate to (and for which you won't create new sibling terms) - many are descendants...

@ValWood These are all the annotations I find for 'regulation of transcription in response to x' https://docs.google.com/spreadsheets/d/1dXW1T7ZoURb5Wll_pR7FnGfxGMwIY7HT-UnI12lKTyE/edit?usp=sharing Pombase has 74 in that list (my previous query was probably too wide)....

Well hopefully not more than very 10 years ! @srengel Should we then obsolete terms that are not or seldom used, to at least avoid creating new annotations ?

These 55 terms all have 0 annotations; I'll send an obsoletion notice: Label ---- negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter...

Dear all, The proposal has been made to obsolete the following pre-composed terms: GO:0100052 negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter...

Also: * GO:0036083 positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter (annotations changed: https://github.com/geneontology/go-annotation/issues/2591) * GO:1900478 positive regulation of sulfate...

I've done the first batch. I'll check what annotations are left at the next release and do another group of terms. Pascale

A few more terms: - [x] GO:1900460 negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter https://github.com/geneontology/go-annotation/issues/2633 - [x]...