paturley

Hi Paloma, Fixing up the beta-se functionality is on our list of things we'd like to do, but like everyone, we are also swamped with other work, so I don't...

Hi Divya, No updates here, though we are working on implementing MTAG into the MAMA software, which should be more robust to these sorts of issues, so hopefully there is...

Sorry,I don't understand your question. Can you explain what you need in more detail? On Wed, Jan 25, 2023, 7:03 AM NKC_IARI ***@***.***> wrote: > Where can I get the...

Sounds like James found a workaround, though this isn't implemented in the current version of MTAG, so you'll have to implement it in your local copy. We unfortunately don't have...

Hi Allen, MTAG also uses the N as a proxy for the SE^2 in the calculation. If you are pretty confident that the sample size is constant across SNPs, you...

You know, as I'm thinking about this harder, I think this is wrong, but I'm not sure what the right way forward is. Let me think about this a bit....

So the problem with using that formula is that it assumes that the phenotypic variance is one, which it won't be for a binary phenotype. For a binary phenotype, probably...

Sorry, the F is the prevalence of the binary phenotype. Unfortunately, I don't have bandwidth to test this myself right now (and probably not in the near future). On Wed,...

I think that using the total cases and controls in the data (rather than by SNP) is reasonable unless you have reason to believe that it would vary a lot...

Curious, though maxFDR is going to struggle with 9 traits even if you get it running. Can you attach the full log file? On Mon, Feb 12, 2024 at 6:08 ...