paturley

Hello, You are right that having the p-value and the z-stat is redundant, but the software uses it as a robustness check to make sure it is reading in the...

I'm mostly just surprised you are getting p values that small. Either they must be for super rare alleles or they have implausibly large effect sizes. Can you verify that...

Hi Wallace, I'm sorry I haven't responded to your issue yet. It has been a crazy week. I'll get to it by the end of the week, if that's OK?...

Hello Wallace, Sorry for the delay on this. Here are a few of my thoughts. The violation of the homogeneous Omega assumption isn't about whether the SNP is highly significant...

Thanks. Case/control data should be fine as long as you use the correct the standard errors that correspond to the log(OR). On Fri, Nov 2, 2018 at 6:19 AM aydzhouyuan...

MTAG does require the MAF column, but you can use allele frequencies from a reference panel if you'd like. On Sun, Nov 17, 2019 at 10:00 PM chenming9453 wrote: >...

Could you attach the full log file, please? It works make it a bit simpler to diagnose what's going on. On Fri, Aug 14, 2020, 7:50 AM yabwei wrote: >...

Ah. It probably makes the most sense to just change the code to filter those variants out. We'll make an update to the software and push that today. On Fri,...

The only case that allele frequency gets used is to transform the summary statistics into standardized or unstandardized units, so using either frequency or MAF should work fine. It also...

It's hard to say. With such a high genetic correlation, I think it's likely fine, but have you done maxFDR calculations yet? On Mon, Jun 28, 2021 at 11:43 AM...