paturley

Hi Xiaofei, There is nothing intrinsically wrong with the median to have a large value. We just included it because, except is rare circumstances, it's likely to be a sign...

Yeah that looks fine to me. It's also possible that the units of your phenotype are very large, which would inflate the expected magnitude of the median beta. When we...

Hi Diana, Do you have a log file for your analysis? Or alternatively, do you know the standard deviation of the phenotype you are analyzing? Patrick On Fri, Feb 18,...

Hello Mahantesh, For the allele frequencies, you can just merge your file with the allele frequencies from a reference file of the same ancestries and that should work fine. For...

Was the GWAS done with a linear probability model or logistic regression? On Tue, Mar 15, 2022 at 11:22 AM Mahantesh Biradar ***@***.***> wrote: > Hi Patrick, thanks for your...

For logistic regression, check out issue #60 . There's a standard formula for effective N in that case.

If you don't have the data, then hopefully they report it in the paper. In many cases, the phenotype has been standardized, which would mean sig2_y=1. On Tue, Mar 22,...

Hello! If you use the meta-analysis option, the files should be identical, so any of them should do. We talked about changing the code so that it only produces one...

Hello Kai, There are a number of filters that MTAG uses based on things like allele frequency, sample size, and other things like that. I believe that the log file...

What happens if you calculate the z-score for your summary statistics and use the Z/N specification? On Mon, May 25, 2020 at 1:15 PM MarioGuCBMR wrote: > Hi, I am...