simaerep
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openpharma
simulate adverse event reporting in clinical trials with the goal of detecting under-reporting sites.
prob_high = ifelse( .data$mean_ae_site_med75 == .data$mean_ae_study_med75, 1, .data$prob_high ) https://github.com/openpharma/simaerep/blob/dd5e9e7d39d20c4069775526ea2303d5c3120175/R/simaerep.R#L417 In this line we are setting the probability to 1 for site means which are equal (==) to study mean....
This release changes defaults according to the latest algorithm improvements. - [ ] not use multiplicity correction by default - [ ] over-reporting default - [ ] consider making inframe...
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simulate adverse event reporting in clinical trials with the goal of detecting under-reporting sites.