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Support of minimap2, bam mem2 and bwa aln

Open agalitsyna opened this issue 1 year ago • 1 comments

Adding an opportunity to select the aligner out of:

  • minimap2 and single-end data https://github.com/open2c/distiller-nf/pull/177
    • requires mapping with parse2 instead of parse
  • bwa mem2 which is a fast optimized bwa mem
  • bwa aln optimized for single end https://github.com/open2c/distiller-nf/pull/171/files

Pros:

  • flexibility for multiple types of data Cons:
  • reduced readability
  • more code and params

agalitsyna avatar Nov 08 '22 00:11 agalitsyna

if you were to add those mapper, would you consider adding chromap as well? In our experience it performs just as well and is significantly faster.

mxw010 avatar Dec 02 '22 20:12 mxw010