Niranj Chandrasekaran

While working on CPJUMP-Stain2, @shntnu and I [observed](https://github.com/jump-cellpainting/pilot-analysis/issues/15#issuecomment-675754131) that the proportion of compounds with a strong signal (percent strong metric) was similar if the analysis was performed with individual channels...

Set epsilon to zero in `RobustMAD`

5

@gwaygenomics You may already know that we sometimes have [had issues](https://github.com/jump-cellpainting/pilot-analysis/issues/15#issuecomment-670640802)(private repo) with `mad_robustize` where one or few features end up being significantly larger than the other features, and then...

Determine epsilon from the data

3

The current implementation of sphering in pycytominer uses a constant value (`1e-6`) for the regularization parameter `epsilon`. https://github.com/cytomining/pycytominer/blob/a5dac9e3fa3cdf61e9607f479ba53eac7fed18b1/pycytominer/operations/transform.py#L25 Sphering performance may improve if the value of `epsilon` is determined directly...