scrnaseq
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Add ATAC-Seq data support
Description of feature
This goes hand in hand with the issue for CITE-Seq (https://github.com/nf-core/scrnaseq/issues/99). Does it make sense to also try to integrate ATAC-Seq data support in the pipeline as well? scATAC-Seq is also supported by Cell-Ranger's 10x. I will test out the pipeline on some real data anyway in a few days.
Yet, since the name is scrnaseq, it might be a bit hard for people to notice that the pipeline can also be used for scATAC-seq data.
I just learned this would require the cellranger-arc
pipeline which seems independent of the regular cellranger command?
So we would probably want to build a separate cellranger-arc
module and support this as a separate aligner ("cellranger-arc" among "cellranger"/"kallisto"/"alevin-fry")? Any other thoughts about how to best implement this?
I think it's the best way to go for multiome. For scATAC alone, you could use cellranger itself. I wanted to implement the cellranger-arc module and am currently working on it.
For scATAC alone, you could use cellranger itself. is this still true? it seems like you need
cellranger-atac
, whereascellranger-arc
handles the multiome data
scATAC data support should work once https://github.com/nf-core/modules/pull/2450 is merged
closing in favor of https://github.com/nf-core/scrnaseq/issues/174