VEP Cache - AWS S3 Access ID Error

Open chan-98 opened this issue 5 months ago • 1 comments

Description of the bug

Getting AWS Access ID error trying to run VEP annotation (with VCF input)

Command used and terminal output

nextflow run nf-core/sarek -profile docker --input SampleSheet.csv --tools vep --outdir results --genome GATK.GRCh38 --step annotate

ERROR ~ The AWS Access Key Id you provided does not exist in our records. (Service: Amazon S3; Status Code: 403; Error Code: InvalidAccessKeyId; Request ID: E5B999QFS2D9YMBY; S3 Extended Request ID: ssHFuX/Vd4Kiwnq4f34/oOBpqsw37LMZBlo8bCd1wKAdy6DrsfxeWFzxy/2K/82e6eFlaHdk2rKntbhIt1nye8IeQjsaR5LC; Proxy: null)

Aug 04 '25 15:08 chan-98

Can you check if you can access s3://annotation-cache ? It should be public

Sep 01 '25 12:09 maxulysse