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It is possible to make "known indels" and "dbsnp" databases optional in this pipeline as was done in Sarek?

Open Jokendo-collab opened this issue 1 year ago • 3 comments

Description of feature

I am working with zebrafish genome and it lacks "known indels" and "dbsnp" databases and I see it is a mandatory requirement in this pipeline. How can one call variants from an organism lacking the above mentioned files?

Jokendo-collab avatar Jan 26 '24 15:01 Jokendo-collab

Maybe you can provide a dummy empty VCF file for now to trick the pipeline?

bounlu avatar Jan 26 '24 15:01 bounlu

Not sure if that can work but I will give it a try

Jokendo-collab avatar Jan 26 '24 15:01 Jokendo-collab

It should work since that VCF will be used to substract the SNPs/indels only. So x - 0 = x meaning that you will get out back what goes in. Need to test to see how that will work though.

bounlu avatar Jan 26 '24 15:01 bounlu