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new module: protein-activity/viper

Open juanesarango opened this issue 9 months ago • 0 comments

Is there an existing module for this?

  • [x] I have searched for the existing module

Is there an open PR for this?

  • [x] I have searched for existing PRs

Is there an open issue for this?

  • [x] I have searched for existing issues

Further Information

Viper is a tool for computational inference of protein activity network and its interactions, useful for precision medicine to understand how drugs are involved in protein pathways.

  • Hackathon Project: https://github.com/nf-core/website/pull/3266
  • VIPER: reference

from the Califano Lab:

"Under the premise that cellular phenotypes not only result from alterations in the genomic code but also depend on the influences of multiscale networks of molecular interactions that regulate gene expression, protein abundance, epigenetic state, and signaling activity. Therefore, understanding how the code embedded in the genome eventually generates cellular phenotypes requires the development of methods for integrating data describing these various levels of activity."

Are you going to work on this?

  • [x] If I'm planning to work on this module, I added myself to the Assignees to facilitate tracking who is working on the module

juanesarango avatar Mar 24 '25 20:03 juanesarango