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Call peak without chip-seq input control.

Open ljw20180420 opened this issue 9 months ago • 1 comments

Description of feature

If there is not chip-seq input control, then the pipeline does not call peaks by macs3. It is hard to find input control on ncbi. It will be useful if the pipeline can call peaks without chip-seq input control.

ljw20180420 avatar Mar 21 '25 12:03 ljw20180420

I totally agree — I'm currently facing the same issue. I'm working on public ChIP-seq datasets that don't include input controls, and it's blocking peak calling with MACS3. It would be really helpful to allow running the pipeline without a control, even if with a warning or reduced stringency. Is there any current workaround?

audrey2000 avatar Jun 11 '25 12:06 audrey2000