Signal always higher in one condition

[Cristinex]

Hi, All,

I have been trapped by a problem which I found that one condition of my data has signals always higher than the other. I discovered this phenomenon by browsing at UCSC genome browser. I get some information from the internet, telling that it could be the result of no normalization. However, to my understanding, the bigwig file outputs by nf-core/atac-seq are all normalized. Do you have any idea about what was wrong?

Appreciated.