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                                            nadineparker

Warning: max number of iterations reached in adjustment procedure. Sigma matrix used is still non-positive-definite

Hi, agreed this is puzzling. The LDSC h2 = 0.2918 (0.0112) and the intercept = 1.0173 (0.0086).

Warning: max number of iterations reached in adjustment procedure. Sigma matrix used is still non-positive-definite

Apologies for the long delayed follow-up. It turned out that there were a number of duplicated SNPs, one with rsid and the other with a variant ID (chr:pos:A1:A2), in the...