mdbarnesUCSD
mdbarnesUCSD
Thanks for sharing the command and files for reproducing the issue. I tested with `chrom_based=False` and a standard matrix was returned and no chrom_based files were generated. I suspect the...
It seems that there are two things that may be happening. If you want a matrix file for the mutations on chromosome Y, then you will need to run `chrom_based=True`....
Please re-open if you are still encountering issues.
The [v1.2.31 release](https://github.com/AlexandrovLab/SigProfilerMatrixGenerator/releases/tag/v1.2.31) resolves the issue of the matrices not being returned. The number of mutation on ChrY can be determine by reading the corresponding files immediately after the SPMG...
I believe that non-chromosome based matrices are being returned in memory, which can be saved to a file. Additionally, matrix generation can be run again with chrom_based=False. If neither of...
Hi @DarioS, SigProfilerAssignment does support structural variants through matrix inputs but you are correct that it does not process structural variants via bedpe inputs. If you do not have a...
The context_type parameter is not relevant for matrix input. The most current version of code is what is hosted in this repository. We will expand the documentation on the README...