mdbarnesUCSD

Please reach out if you are still encountering issues with your run.

Hi @IanVermes, Thanks for reaching about this. We have decided that we will introduce a changelog into our repositories to help communicate the changes across versions moving forward. Regarding your...

Hi @superjw, Thanks for reaching out. We will be looking to modify this behavior in a future release.

Hi @nservant and @superjw, The volume parameter has been added as well as support for the environmental variable "SIGPROFILERASSIGNMENT_VOLUME". The environmental variable takes precedence over the parameter and should be...

The COSMIC signatures as of v3.4 release are supported for contexts SBS96, ID83, DBS78, SV32, CNV48, and RNA-SBS192. The contexts that you see for SBS288, SBS384, SBS1536, SBS4608, and SBS6144...

Yes that is correct, the values in `Assignment_Solution_Activities.txt` are the mutation count associated with each signature per sample.

Please reach out if you have any additional questions.

Hi Ronnie, Could you please send over an input file to reproduce this issue? Thanks!