Kyle McChesney
Kyle McChesney
@MAfustier I was never able to find a resolution for this. I opted for making a dump of the database in columm format and loading into memory as needed. I...
How to apply a protein change to a given amino acid sequence to produce a mutant amino acid sequence
I have a similar use case but expanded to include the use case of having multiple variants. For example if I have 2 SNP variants in DNA space (in which...
How to apply a protein change to a given amino acid sequence to produce a mutant amino acid sequence
@reece thanks for the additional context (and again for all the hard work on the library). I have come up with an approach which solves my current challenge. For reference...
I realize this is stale, but I wanted to add another "voice" to the discussion. I have been working with the hgvs library for the better part of a year...