minimap2
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Soft-Clipping of Deletion
I am currently using minimap2 (v2.24) with the default alignment settings for aligning scaffolds, contigs, and Hifi reads. However, I have come across a peculiar observation. While aligning contigs, instead of correctly identifying a 1bp deletion (as observed in the alignments of scaffolds and Hifi reads), the contig alignment appears to soft-clip the left part of the deletion, as depicted in the figure below.
I would appreciate it if you could shed some light on the underlying reason for this behavior. Additionally, I would like to inquire if there are any specific parameters that can be utilized to "correct" this alignment issue.