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Refining tumor/normal assignment

Open nandobonf opened this issue 3 months ago • 0 comments

Dear authors, I successfully ran Numbat on multiple samples, however in some cases I would need to refine the tumor/normal definition (or eventually remove "noisy" CNV calls such as the BAMP). In the case shown below, for example, it is clear that genotypes 1 and 2 demote normal cells, instead, Numbat only calls genotype 1 as "normal". You can see the Numbat tumor/normal annotation labeled as "type" in the heatmap below. Any suggestions would be highly appreciated. Thanks in advance.

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nandobonf avatar Oct 29 '24 14:10 nandobonf