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Profiling tool for Mycobacterium tuberculosis to detect ressistance and strain type from WGS data

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Hi Jody, I used "mamba create -n tb-profiler tb-profiler" to install tb-profiler v4.3.0. I ran "tb-profiler profile -1 SJ_2012_0029_R1.fastq.gz -2 SJ_2012_0029_R2.fastq.gz -p SJ_2012_0029", and I got Traceback (most recent call...

Hi Jody, I get this error while running profiler: set -u pipefail; trimmomatic PE -threads 1 -phred33 /tmp/flytek_8nxtt7/local_flytekit/dd7a9c79cfb126a676d84d21f5aebf89/ERR3077930_1.fastq /tmp/flytek_8nxtt7/local_flytekit/e80258887acb296b57e61d96d65e4c00/ERR3077930_2.fastq -baseout .//root/tbprofiler/pfiles LEADING:3 TRAILING:3 SLIDINGWINDOW:4:20 MINLEN:36 Command Failed! Please Check!= How...

Dear Jody, I noticed that in v4.2.0 the lineage family is missing in the text report: ``` Summary ------- ID: xxx Date: Sun Jul 3 14:15:29 2022 Strain: lineage2.2.1 Drug-resistance:...

i got the following error while running tb-profile on a BAM file Using gff file: /home/st1compgen/anaconda3/envs/tb-profiler/share/tbprofiler/tbdb.gff Using ref file: /home/st1compgen/anaconda3/envs/tb-profiler/share/tbprofiler/tbdb.fasta Using ann file: /home/st1compgen/anaconda3/envs/tb-profiler/share/tbprofiler/tbdb.ann.txt Using barcode file: /home/st1compgen/anaconda3/envs/tb-profiler/share/tbprofiler/tbdb.barcode.bed Using bed...

This is a fringe issue that I ran into when running TB-profiler through a conda installation that is shared by multiple users. I just want to write it down for...

### Summary Mixed infections can cause difficulties when analysing wgs data. Improved support for mixed infection data as well as mutation phasing will be implemented.

Hi Jody When running TBProfiler (using --vcfprofile) on data generated by lofreq, the frequencies of the variants are computed incorrectly. If there are two variants on the same positions (see...

### Summary There is currently no support for generating reports based on longitudinal data. An new module will be developed to look characterise lineage and drug resistance patterns between sequential...

### Summary A new data extraction module will be build for more flexible and customisible generation of reports as well filtering and searching across multiple results.