hrp1000

Many thanks for the rapid response. Having now tried running with hhblits_omp, I can see that a HEWL_a3m_wo_ss.ffindex file is created (of course, with the argument I gave to the...

I've been busy with other things and have come back to this. Essentially, it's a continuation of the same problem. I've now created ~65,000 sets of 6 files from my...

Just checked with version 3.3.0 (built last August) - I get the same issue, i.e. the gap is shifted by one amino acid.

Also tried with .hhm file created from a .fasta file with the "missing" residues represented with "-". Same result - the gap in the alignment is shifted by one residue.

Any response of any kind would be gratefully received!

Hi Daniel see attached… I found (what looks like it links to) a HIgh Sierra installer at https://support.apple.com/kb/DL1946?viewlocale=en_US&locale=en_US Harry > On 11 Jan 2022, at 16:37, Daniel Paley ***@***.***> wrote:...

Just noticed that I do seem to have numpy 1.21.2... > On 11 Jan 2022, at 16:44, Harry Powell ***@***.***> wrote: > > Hi Daniel > > see attached… >...

You’ll have to help me here - how do I downgrade/upgrade with conda? I tend to use it purely with defaults and let it do what it wants... > On...

just “solving environment” :-) H > On 11 Jan 2022, at 16:59, Daniel Paley ***@***.***> wrote: > > > Sorry about that :) After activating the environment with cctbx in...

Hi Daniel It’s still going with 1.21.5 - it seems to have "failed with initial frozen solve” a couple of times. I’ll wait until it fails compeletely, then try mamba....