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cde.error.models in batch

Open ghost opened this issue 7 years ago • 2 comments

Do you think in scde.error.models you should also take batch effect into consideration?

ghost avatar Mar 03 '18 13:03 ghost

Yes, if you have batch information, you can provide that into the groups parameter so that error-modeling is done in a batch-specific manner.

Jean Fan, PhD Bioinformatics and Integrative Genomics NCI F99/K00 Post-Doctoral Fellow Zhuang Lab | Harvard University 12 Oxford St, Naito 031, Cambridge, MA 02138 web: jef.workshttp://jefworks.com/

On Mar 3, 2018, at 8:52 AM, Poorya Parvizi <[email protected]mailto:[email protected]> wrote:

Do you think in scde.error.models you should also take batch effect into consideration?

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JEFworks avatar Mar 05 '18 13:03 JEFworks

But the problem is, my single cells have two conditions which both exist in different batches. Do you mean in this case I should have 4 groups?

ghost avatar Mar 05 '18 13:03 ghost