drivenbyentropy

Details regarding modified fraction calculation from per-read statistic files

3

Hi, I am trying to reproduce the calculation of the (dampened) modified fraction provided by tombo using the per-read statistic files produced by `tombo detect_modifications model_sample_compare` for a subset (clusters)...

Size difference in per read statistics file when running `tombo detect_modifications model_sample_compare` with different `multiprocess-region-size` values

2

Hi, During a benchmarking procedure to assess the best parameter set for the hardware environment I am running `tombo` in, I noticed that the per read statistics files result with...

Hi, I noticed that the heatmap figure in the [tombo docs](https://nanoporetech.github.io/tombo/modified_base_detection.html#id3) is not showing. I suspect it was not linked correctly. Thanks.

Currently, we use the default parameters of RNAFold for folding. Adding the possibility to configure these, would allow for a more fine graded structure analysis.

Hi, When running bonito with a custom trained modified base model and specifying the ```--modified device``` option, it fails at runtime with the following error: ``` > reading pod5 >...

```get_io_reads()``` fails with ```Move table discordant with signal``` on some reads

3

Hi @marcus1487, I am running into an issue that I was hoping you could provide some insight into: I have a dataset from a P2 sequencer that was basecalled and...