Douglas B Craig

Related to this... when using scale() the Z-score is by column, which means each sample (or element of a time series) is normalized _within_ the sample. However, the counts from...

Lorena, Thank you for the prompt reply. It was very helpful. Just to further clarify... you say the cluster calculation is on the original expression values (not scaled values), so...

Okay, that makes more sense. Sorry, I had assumed a Euclidean distance measure for clustering instead of the correlation that you had already mentioned. Thanks for patiently explaining this to...