gffutils
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improve gffwriter
How to write out to file is not currently obvious (xref #37, #88). Having a class or function to handle this will help with discoverability and will be an obvious place to write docs. Specifically, make sure any directives get written out to file first.
This would also be a good place to handle GTF/GFF/refflat conversions, similar to Bio.SeqIO.
I would like to up vote this as a really useful function