Chris Bielow

Results 34 issues of Chris Bielow

## Platform - SeqAn version: latest - Operating system: NA - Compiler: NA ## Question Imagine you want to search for peptide sequences (aka needles/patterns) in a protein (text) using...

question

e.g. running OMSFile_test on Windows ``` QSqlDatabase: QSQLITE driver not loaded QSqlDatabase: available drivers: QSqlDatabase: an instance of QCoreApplication is required for loading driver plugins Error: Caught unexpected exception of...

I stumbled over the following problem recently, which deletes the move-assignment operator for classes which would really benefit from it. The underlying reason is simply that a class member or...

Performance

## Description Starting out with a simple change "get rid of Plot1DCanvas::isMzToXAxis()", turned out to be a huge daisy chain of changes, which cannot be done incrementally. So this PR...

related to https://github.com/OpenMS/OpenMS/issues/5318 When opening TOPPView on Windows, and closing it again TOPPView crashes at: ``` > OpenMS_GUId.dll!OpenMS::TVToolDiscovery::waitForParams::__l2::() Line 88 C++ OpenMS_GUId.dll!OpenMS::TVToolDiscovery::waitForParams() Line 75 C++ OpenMS_GUId.dll!OpenMS::TOPPViewBase::addToolParamsToIni_() Line 1668 C++ OpenMS_GUId.dll!OpenMS::TOPPViewBase::savePreferences()...

This PR adds support for interactive plots in the HTML report via plotly. There are still some glitches (with legend labels mostly) -- so regard this as work-in-progress.

some pointers here: https://www.mcponline.org/content/5/4/652 The corresponding QualScore tool is available in TPP, but not maintained since its publication...

this should allow the user to spot weird mass offsets (from unidentified PTMs or non-peptide signals)

If low MS/MS identification rates are observed without clear indications of origin (e.g. intensities are high, samples are mass-calibrated, etc) it might be beneficial to re-run MaxQuant allowing more variable...

e.g. using R^2 could hint at non-specific sample loss in some samples, i.e. overall reduced reproducibility and false positive biomarkers, due to different sample handling and materials (tubes, addition of...