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Thanks @qoiopipq I am unable to use pData function on Seurat object. ```R > pData(seuratObj) Error in (function (classes, fdef, mtable) : unable to find an inherited method for function...

Hi @kdkorthauer Thank you very much for your reply. I tried `minInSpan=10`, bpSpan values between `5,000` to `10,000`, maxGapSmooth between `10,000` and `100,000` and `maxGap=5000`. I was unable to get...

Hi @kdkorthauer Thank you for more insights. I have been using `cutoff = 0.01`. I have following experimental design and I would like to find methylation different between group A...