billzt

希望能给macOS弄个M1版本

2

现在这个intel版本太耗电了

output gzipped data

3

If the input is gzipped data, the output should be automatically gzipped. Otherwise users would encounter large files

Add additional limitations for long query sequence

3

Some end users that are not familar with bioinformatics might use long query sequence (>1Mb DNA sequences). Usually this is meaningless and instead would take long running time. It is...

limit query size and customize /tmp dir

3

We set up a sequenceserver app for public and usually the /tmp dir would ran out of disk storage because of long DNA query sizes resulting in large temporary files....

multiple samples analysis: how to merge barcode files?

2

In FAQ it writes the following codes to start multiple samples analysis: ``` > file.list = c("atac_v1_pbmc_5k.snap", "atac_v1_pbmc_10k.snap"); > sample.list = c("pbmc.5k", "pbmc.10k"); > x.sp = createSnap(file=file.list, sample=sample.list); ``` However...

In which situation would the .htaccess file being replaced?

3

I've just encountered (and luckily solved) a servious bug related with `.htaccess`: In order to make my website faster (using apache, including JBrowse and other situations), I use gzip compressing...

Enhancer in GFF

7

Supporting a GFF file like this: ``` 1 araport11 mRNA 52061 54689 . + . ID=transcript:AT1G01110.1 1 araport11 exon 52061 52730 . + . Parent=transcript:AT1G01110.1;Name=AT1G01110.1.exon1;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=AT1G01110.1.exon1;rank=1 1 araport11 five_prime_UTR 52061 52730...

running speed is too slow, only using one CPU

6

the reference genome has 26 chrs, 2.4G size. And the sequence coverage is about 100X. Currently gencore keeps running for >15 hours and still doesn't stop. I found that gencore...

What is the minimum required read length?

2

I conducted a simulation. When my read length is 89bp, it outputs expected fusions. However when I use read length of 85bp. There are no results. The main change is...

I can't see such options