Bede Constantinides

Results 66 comments of Bede Constantinides

Hi there, 1. Hostile offers equal or higher retention of bacterial reads than other host read removal approaches with the default index (`human-t2t-hla`), but using `human-t2t-hla-argos985` can slightly improve this...

No problem :) 1. Correct 2. Ideally yes. If enabled, trimming would reduce the number of human reads removed by Hostile. 3. I am not sure what is common practice...

Hey Sam, thanks for opening this. Agree it would be nice to have. When I get time I'll investigate whether it's straightforward and how much it improves performance. Can imagine...

Hey Sam, Sorry for delay. I've just had a look and am deciding whether to implement it. Streaming the reads through the Python interpreter adds some overhead, but not as...

Thanks @ddooley ! I'm encountering this issue with LinkML 1.5.0 installed with Python 3.11 (conda) on MacOS 12.6, running under Rosetta (x86_64) on Apple silicon. ``` % linkml-convert --version linkml-convert,...

Thanks so much @cmungall ! I had tried something along these lines already which triggered further errors – perhaps you can suggest where I was failing? `developers` now reads as...

Thank you all so much! Working great, and I'm cracking on with integrating LinkML into our project 🙏

Thank you all for helping so much here. I got a solution working well until LinkML `1.5.3`, given [this model](https://github.com/pha4ge/primer-schemes/blob/056e8f537e70a8400fdad43c29fb2e2c6ba8cb47/schema/primer_scheme.yml) and [these data](https://github.com/pha4ge/primer-schemes/blob/056e8f537e70a8400fdad43c29fb2e2c6ba8cb47/sars-cov-2/midnight/v1/info.yml): With LinkML `1.5.2`: _Works as expected without...