Benjamin Buchfink

Loading in the database sequences may still take 10%-20% longer when using a BLAST db, but the overall impact on performance should be minimal.

> > > Hello > I failed when trying to compile Diamond (my os is quite old, I can not use the binaries `version 'GLIBC_2.17' not found`...) > So I...

> > > Here is a gist file with my compilation issues: [Diamond 2.0.8 compilation issues. (CentOS release 6.6 (Final)) ](https://gist.github.com/FredericBGA/4ac1456f19678a7226914bcbc3d6a84c) > > I hope you will be able to...

Did you just run makeblastdb on a fasta file or something else? It may not work yet for aliased databases.

It works for me when using a BLAST db created by makeblastdb. This error likely means the database has a sparse OID range for some reason, like alias databases do....

> > > I used a SEED fasta file and turned it into a blast database and while running it seems to look ok but after a while it encounters...

The conda version does not yet support this, you can download the prebuilt binary: http://github.com/bbuchfink/diamond/releases/download/v2.0.9/diamond-linux64.tar.gz When compiling from source, some additional steps need to be taken to enable blast db...

Since v2.0.10, using a BLAST database now requires a `diamond prepdb` call. But in return, performance for loading in the database has been largely improved, and using a BLAST database...

> > > I'm also getting the no alias/index error when calling `diamond prepdb -d nr` on my newly downloaded nr db: > > > Error: NCBI C++ Exception: >...

Hi, would it be possible to make your input file available to me so I can reproduce the problem?