register error in runSCENIC_2_createRegulons

[hsd676]

I keep getting the "Error in UseMethod("register", x) : "register" has no method "c('MulticoreParam', 'SnowParam', 'BiocParallelParam', 'envRefClass', '.environment', 'refClass', 'environment', 'refObject')" for the target object" error.

I have already tried resetting core parameters = 1. Please help. I am stuck.

runSCENIC_1_coexNetwork2modules(scenicOptions) 20:36 Creating TF modules Number of links between TFs and targets: 3504334 [,1] nTFs 872 nTargets 9437 nGeneSets 4902 nLinks 4257482 runSCENIC_2_createRegulons(scenicOptions, coexMethod=c("top5perTarget")) Error in runSCENIC_2_createRegulons(scenicOptions, coexMethod = c("top5perTarget")) : Parameters are useless, (coexMethod = c("top5perTarget")) runSCENIC_2_createRegulons(scenicOptions) Error in UseMethod("register", x) : "register" has no method "c('MulticoreParam', 'SnowParam', 'BiocParallelParam', 'envRefClass', '.environment', 'refClass', 'environment', 'refObject')" for the target object

Anyone have the same error? Please share your solution, Thank you!

[ruoyeruolan]

Has your error been solved?

[vida-change]

Has your error been solved?

[JokerOuO]

I have the same problem. I found was caused by a conflict between the register function of the NMF package and the BiocParallel package. Run detach("package:NMF") before runSCENIC_2_createRegulons function or change register(MulticoreParam(nCores), default = FALSE) to BiocParallel::register(MulticoreParam(nCores), default = FALSE) in the source code.