Toros

unknown severity: splice_polypyrimidine_tract_variant & splice_donor_region_variant

1

When using Ensembl VEP version 105 we get following vcf2db warnings: ``` [2022-07-07T10:19Z] WARNING: unknown severity for 'C|splice_donor_region_variant&intron_variant|LOW|NOC2L|ENSG00000188976|Transcript|ENST00000327044|protein_coding||8/18|ENST00000327044.7:c.888+4C>G|||||||rs13303056|1||-1||SNV|HGNC|HGNC:24517|YES|NM_015658.4||1|P1|CCDS3.1|ENSP00000317992|Q9Y3T9.182||UPI000041820C|||Ensembl||G|G|||||||chr1:g.953778G>C||0.829|0.9135|0.9365|0.9523|0.9172|0.8238|0.9333|0.9321|0.8235|0.9508|0.9351|0.9215|0.9599|0.9413|0.9357|0.9192|0.9599|gnomAD_FIN||||||||||NOC2L:K296int|1&1&4||NOC2L&NM_015658.3&c.888+4C>G|||||INTRON_END:953781&DONOR_ESS:4&DONOR_ISS:4&EXON_END:953892&DONOR_GERP_DIFF:NA&DONOR_ESE:45&MUTANT_DONOR_MES:8.46099459345687&EXON_START:953782&DONOR_ISE:20&BRANCHPOINT_DISTANCE:NA&INTRON_START:953289&DONOR_MES_DIFF:-0.0169218360392236|8.461|-0.017|8.444|splice_donor_region_variant' with effect 'splice_donor_region_variant' [2022-07-07T10:19Z] Please report this on github with the effect-string...