QLZhouBio

> Hi, thanks for this question. AmpliconSuite-pipeline is not designed for analysis with whole genome bisulfite sequencing, only paired-end whole genome sequencing. I am not currently aware of any existing...

> I am not an expert in WGBS, however the conversion of unmethylated cytosine to uracil, and subsequently to thymine will likely reduce the quality of alignments, creating challenges in...

> Hi, the pipeline is primarily going to use mapping quality scores from the bam. These are based on how well the read aligned to the reference. This is used...