Read counts not being filtered

[MarcosDomingues97]

Hi, I ran corset in a single sample with the default parameters and got clusters with read counts below 10, some of which with zero counts inclusively. Is this to be expected?

Thanks in advance.

[nadiadavidson]

Hi, Yes, this comes about because reads which are shared between more than one cluster get randomly assigned to a cluster. Meaning that a cluster may have originally had 10 or more reads mapping, but some of these are reassigned to avoid double counting.

There are a few related threads on this in https://groups.google.com/g/corset-project?pli=1 and closed issues which you might like to look at also. Cheers, Nadia.