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in overlap position, gencore doesn't reset quality

Open wyy1234-github opened this issue 2 years ago • 0 comments

hi , in the document : In the overlapped region, if a base and its pair are mismatched, its quality score will be adjusted to: max(0, this_qual - pair_qual), but i find the quality score doesn't reset, image the 134G8 means G>T in the first read, and the second read is still G, the quality of this position are both D(Q35), so G>T mutation is called by vardict since the quality seems good.

wyy1234-github avatar Mar 24 '23 05:03 wyy1234-github