BioPhi
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Merck
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody seque...
It would be nice to be able to navigate between all results without having to go back to the result table page
While using humanization module at https://biophi.dichlab.org/, I found the sequence of IGKV2-30*01 was different from the sequence from http://www.imgt.org/download/GENE-DB/IMGTGENEDB-ReferenceSequences.fasta-AA-WithoutGaps-F+ORF+inframeP .The second sequence was copied from the biophi web page. ...
E.g. Sapiens*1-*5 + Vernier CDR graft + Vernier CDR graft with 1 Sapiens iteration
We should provide instructions on providing the OASIS_DB_PATH and mounting the directory so that the database can be accessed when running through `docker run` or `docker-compose`.
Result tables should be sortable, now it's implemented in javascript, it only works if we have
We should display the number of mutations, and separately number of Vernier mutations. We should also report the % preservation values.
Hi, Thanks for open sourcing this work- it's awesome! Not as much of an issue as a request. Could you open source the humanization benchmark that you use in the...
Black arrows in Vernier zones and CDRs, black bold residues that are mutated
Enable collecting multiple designed sequences, adding names to them and exporting them in a single FASTA file.