archs4 icon indicating copy to clipboard operation
archs4 copied to clipboard

ENSG genes when using gene_symbols

Open malonzm1 opened this issue 1 year ago • 2 comments

Hi,

When I use the R script (h5read(destination_file, "meta/genes/gene_symbol")) the matrix generated includes genes with prefix ENSG along with regular gene symbols. Why is this?

Thanks and good day.

malonzm1 avatar Apr 27 '23 08:04 malonzm1

This is an issue with the ensembl annotation. Some genes do not have an official gene symbol. We use the ensembl id as a placeholder in this case.

lachmann12 avatar Apr 27 '23 13:04 lachmann12

When I run kallisto with the script that generates identical output as elysium/archs4 there are no genes with prefix ENSG (the output with ENSG genes include > 60,000 genes while the output without ENSG genes include > 30,000 genes). Is it possible to make the output from kallisto the same (>60,000 genes)?

malonzm1 avatar Apr 28 '23 05:04 malonzm1

you can use archs4py to mimic the output now

lachmann12 avatar Jun 07 '24 18:06 lachmann12