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[Independent Enrichment Analysis] Bug in background?
I've recently started using your Appyter for Independent Enrichment Analysis to analyze the Enrichr catalog with a costume background.
But because I kept getting very large odds ratios and very small p-values I got suspicious. Therefore I tested the first 10 genes of the 2019 Human WIkiPathway NRF2 pathway WP2884
using a background of the 20 first genes in the gene set. The result can be found here. Ass seen from the Notebook the odds ratio for the is NRF2 pathway WP2884
is calculated to be Inf
and the p-value is 6.56e-32
. That does not seem like it should be the case if the background was considered?
Did I input the genes wrongly or something similar?