SimkaMin output file symmetry

[hjruscheweyh]

Dear SimkaMin Dev,

I recently stumbled upon your Simkamin tool and tried to use it to compare my 4000 datasets against each other to get information on the similarity of these samples.

I found something odd in the output matrices. They don’t seem to be symmetric. Where the upper triangular contains mostly values between 0.0 and 1, the lower triangular matrix contains mostly but not exclusively zeros. I would like understand if the lower triangular matrix would be empty but a non-symmetric output is strange.

In fact it seems that there is always a subpart that is symmetric but its mostly not.

I attached a screenshot of parts of the matrix.

Do you know what to do with this information? Should I only use the column-based distances?

Best and thanks, Hans