Devlin Moyer

icon indicating a website link https://orcid.org/0000-0002-6997-9531

icon location Boston, MA icon location Recent bioinformatics PhD graduate with experience in metabolic modeling and general 'omics data analysis and manipulation

Results 44 comments of Devlin Moyer
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GPR curation for Glycerolipid metabolism/Glycerophospholipid metabolism/Fatty acid oxidation

It is definitely accurate to associate ACOX1 (`ENSG00000161533`) with `MAR02818` (sources: [1](https://link.springer.com/article/10.1023/A:1022540030918), [2](https://www.annualreviews.org/content/journals/10.1146/annurev.nutr.21.1.193)). We decided to make all of the peroxisomal acyl-CoA oxidation reactions reduce FAD to FADH2 instead of...

GPR curation for Glycerolipid metabolism/Glycerophospholipid metabolism/Fatty acid oxidation

the AI is right about ACOT4 (`ENSG00000177465`) not belonging in the GPR of `MAR03387`, but all of the other genes except SLC27A2 (`ENSG00000140284`) should also be removed, because that reaction...

GPR curation for Glycerolipid metabolism/Glycerophospholipid metabolism/Fatty acid oxidation

yep sorry that was a typo; I meant `MAR03387`

GPR curation for Acyl-CoA hydrolysis, Acylglycerides metabolism and Nicotinate and nicotinamide metabolism

The AI is wrong about `ENSG00000136881` (BAAT) being unable to catalyze `MAR00210`, `MAR00242`, `MAR00324`, `MAR00354`, `MAR00426`, and `MAR00438`; [this paper](https://doi.org/10.1074/jbc.M300987200) showed that BAAT is capable of acting on unsaturated acyl-CoAs...