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Pan-genome wide association studies

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when we used scoary to analysis more then 10000 genomes, the analysis process end at "Calculating max number of contrasting pairs for each nominally significant gene" in Terminal, and only...

==== Scoary started ==== Command: /Users/nondumisondhlovu/opt/anaconda3/bin/scoary -g gene_presence_absence.csv -t case.csv -s 15 Reading gene presence absence file CRITICAL: Traceback (most recent call last): File "/Users/nondumisondhlovu/opt/anaconda3/lib/python3.8/site-packages/scoary/methods.py", line 359, in Csv_to_dic_Roary header[startcol]...

[parsnp.vcf.txt](https://github.com/AdmiralenOla/Scoary/files/8141166/parsnp.vcf.txt) Dear Author, I am trying to do a test GWAS using SNPs for 12 strains of Gallibacterium, fitting different antibiotic resistance binary vectors. If I understand correctly, Scoary can...

As originally reported by @dutchscientist in #53 , Scoary currently throws a ``` RuntimeError: maximum recursion depth exceeded while calling a Python object ``` when attempting to perform pairwise comparisons...

bug

Hi, I'm new to using scoary and am running into an issue. Here is the full error that scoary gives me: `Traceback (most recent call last): File "/home/hcm59/miniconda3/envs/scoary/bin/scoary", line 8,...

Dear @AdmiralenOla Under `Coming soon`, you list `Support for non-binary traits`. This could be of interest to me. What approach are you thinking of? (Simply binarizing continuous traits?) What use...

help wanted
question

I have a very basic question about how the `--collapse` flag determines grouping. Does it collapse genotypes that have the *exact* same distribution across all the samples, or is some...

enhancement

Should be fairly simple to allow internal node labels in the newick file. Although this does not impact results, there is no reason for the program to crash.

bug

Hi there! Is there a way for scoary to generate a collapsed gene absence/presence matrix similar to the --write_reduced flag? Thanks!

I got the CSV files of all trait related genes. How do I get the important genes in all trait files?