Matthew Fidler

I could submit a pull request for the s3 method of `vpc`. It is simple enough. Ron already merged my pull request for a s3 `vpc` method so all 3...

I will submit something once https://github.com/ronkeizer/vpc/issues/46 is resolved.

My solution in the past was to subset to individuals with one observation and plot that dataset with points. (FYI)

Hi @thomasjsln; I suggest you post on the nlmixr github issue tracker. https://github.com/nlmixrdevelopment/nlmixr/

For dynamic transform of both sides, I suppose I could add the objective function correction using a new ofv that relies on `ofv_fim` https://github.com/andrewhooker/PopED/blob/master/R%2Fofv_fim.R But I don't think it is...

> Is fixing the add.err component equivalent to what is done? Looking through the examples this is a clear no. I guess the fixed sigma trick that works in NONMEM...

I also noticed that the prediction functions return DV so there must be some sort of DV prediction. So dynamic transform of both sides won't work 100% by simply transforming...

I also noticed there is an example (example 8) that sort of has this transformation built in for log-values. For now, in the case of dynamic transform of both sides,...

Thanks Andy

Thanks Andy, Possibly for both. `rxode2` calculates these for `nlmixr2` focei and I thought they would be useful in both FIM calculation. I didn't see a hook so I didn't...