HapHiC
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Perform not so good for haplotype mixed assembly
Hi,
I am trying to use HapHiC to anchor a haplotype-collapsed genome (hifiasm p_ctg), and I found that HapHiC perform not so good, especially contig ordering, HiC data was mapping following HiC-Pro 3 pipeline
here is HapHiC results heatmap
and here is EndHiC + manully curation results heatmap
If you need hic (or bam) and contig data for testing, I will upload to baidu netdisk and send you an e-mail (for tesing only).
Best, Kun